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Thursday, May 24, 2018

Microrheology, advances in methods and insights

Qiuyang Xia, Huining Xiao, Yuanfeng Pan, Lidong Wang

Microrheology is an emerging technique that probes mechanical response of soft material at micro-scale. Generally, microrheology technique can be divided into active and passive versions. For active microrheology, a user-controlled force, e.g. magnetic force, electrostatic force, optical tweezers etc., is applied to embedded particle in medium of interest, and the particle motion under this force is tracked. For passive microrheology, the embedded particles only move due to thermal fluctuations in the medium, i.e. Brownian motion, and their trajectories are tracked and analyzed. After Mason's seminal paper that developed reliable theory to calculate the relation between viscoelastic property and Brownian motion of embedding particles, corresponding methods and equipments to track particle Brownian motion both in laboratory and commercially available, together with software for data analysis. During last two decades, extensive efforts have been paid to improve both the experiment techniques and data analysis methods, especially about how to link consequential particle positions into trajectories. Also, some insights have been revealed in soft matter system using this technique. In this review paper we attempt to go through the advances in experiment techniques and data analysis methods developed in last ten years along with some recent results obtained from these methods.

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