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Thursday, January 25, 2018

Optical Tweezers: Fundamentals and Some Biophysical Applications

Kamal R.Dhakal, Vasudevan Lakshminarayanan

Electromagnetic radiation changes its momentum when it interacts with small particles and a gradient force is experienced by the particle. This can be utilized to manipulate microscopic particles in an optical trap and is commonly referred to as optical tweezing. Optical tweezers are used as multifunctional tools in a myriad of applications such as micromanipulation, nanofabrication, biological studies of DNA, cells, biological micrometers, etc. This chapter will discuss the basic theory of optical tweezers (both wave theoretical and ray optics approximation) and provide examples from biomedical science and nanotechnology.

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