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Wednesday, March 6, 2013

The bystander effect in optically trapped red blood cells due to Plasmodium falciparum infection

Apurba Paul, Rani Pallavi, Utpal S. Tatu and Vasant Natarajan

In a previous study of the properties of red blood cells (RBC) trapped in an optical tweezers trap, an increase in the spectrum of Brownian fluctuations for RBCs from a Plasmodium falciparum culture (due to increased rigidity) compared with normal RBCs was measured. A bystander effect was observed, whereby RBCs actually hosting the parasite had an effect on the physical properties of remaining non-hosting RBCs.
DOI

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