Jaekwon Do , Robert Schreiber , Andrey A. Lutich , Tim Liedl , Jessica Rodríguez-Fernández , and Jochen Feldmann
Designing nanoscale objects with the potential to perform externally-controlled motion in biological environments is one of the most sought-after objectives in nanotechnology. Different types of chemically and physically-powered motors have been prepared at the macro- and microscale. However, the preparation of nanoscale objects with a complex morphology, and the potential for light-driven motion has remained elusive to date. Here, we go a step forward by designing a nanoscale hybrid with a propeller-resembling shape, which can be controlled by focused light under biological conditions. Our hybrid, hereafter ‘Au@DNA-origami’, consists of a spherical gold nanoparticle with self-assembled, biocompatible, two-dimensional DNA sheets on its surface. As a first step towards the potential utilization of these nanoscale objects as light-driven assemblies in biological environments, we show that they can be optically trapped, and hence translated and deposited on-demand, and that under realistic trapping conditions the thermally-induced dehybridization of the DNA sheets can be avoided.
DOI
No comments:
Post a Comment