Tanuj Aggarwal, Hullas Sehgal, and Murti Salapaka
Feedback enhanced optical tweezers with position regulation capability enable detection and estimation of forces in the pico-Newton regime. In this article we delineate the fundamental limitations and challenges of existing approaches for regulating position and force estimation in an optical tweezer. A modern control systems approach is shown to improve the bandwidth of force estimation by three to four times which is corroborated experimentally.
DOI
Feedback enhanced optical tweezers with position regulation capability enable detection and estimation of forces in the pico-Newton regime. In this article we delineate the fundamental limitations and challenges of existing approaches for regulating position and force estimation in an optical tweezer. A modern control systems approach is shown to improve the bandwidth of force estimation by three to four times which is corroborated experimentally.
DOI
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