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Tuesday, February 2, 2010

Displacement and Force Measurements with Quadrant Photodetector in Optical Tweezers

Guo Hong-Lian, Liu Chun-Xiang, Li Zhao-Lin, Duan Jian-Fa, Han Xue-Hai, Cheng Bing-Ying and Zhang Dao-Zhong

A technique of displacement and force measurements with a photodiode quadrant detector in an optical tweezers system is presented. The stiffness of optical trap is calibrated and the leukemia cell membrane tension is measured. The results show that the optical tweezers combined with the quadrant detector is a very useful tool for detecting the displacement and force with a millisecond-order response.

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