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Monday, April 27, 2009

Optical microassembly platform for constructing reconfigurable microenvironments for biomedical studies

Peter John Rodrigo, Lóránd Kelemen, Darwin Palima, Carlo Amadeo Alonzo, Pál Ormos, and Jesper Glückstad

Cellular development is highly influenced by the surrounding microenvironment. We propose user-reconfigurable microenvironments and bio-compatible scaffolds as an approach for understanding cellular development processes. We demonstrate a model platform for constructing versatile microenvironments by fabricating morphologically complex microstructures by two-photon polymerization (2PP) and then assembling these archetypal building blocks into various configurations using multiple, real-time configurable counterpropagating-beam (CB) traps. The demonstrated capacity for handling feature-rich microcomponents may be further developed into a generalized microassembly platform.

DOI

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